David H Broide Selected Research

Asthma (Bronchial Asthma)

1/2023	Lymphotoxin beta receptor signaling directly controls airway smooth muscle deregulation and asthmatic lung dysfunction.
1/2022	Insights into the biology of IL-9 in asthma.
9/2019	Genes and Pathways Regulating Decline in Lung Function and Airway Remodeling in Asthma.
1/2019	Airway innate lymphoid cells in the induction and regulation of allergy.
1/2018	Orosomucoid-like 3 (ORMDL3) upregulates airway smooth muscle proliferation, contraction, and Ca2+ oscillations in asthma.
1/2018	Does reduced zona pellucida binding protein 2 (ZPBP2) expression on chromosome 17q21 protect against asthma?
10/2017	Rhinovirus Infection of ORMDL3 Transgenic Mice Is Associated with Reduced Rhinovirus Viral Load and Airway Inflammation.
1/2017	Cutting Edge: Targeting Epithelial ORMDL3 Increases, Rather than Reduces, Airway Responsiveness and Is Associated with Increased Sphingosine-1-Phosphate.
1/2017	Chromosome 17q21 Genes ORMDL3 and GSDMB in Asthma and Immune Diseases.
1/2017	Leukotriene C4 Potentiates IL-33-Induced Group 2 Innate Lymphoid Cell Activation and Lung Inflammation.

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David H Broide Research Topics

Disease

49	Asthma (Bronchial Asthma) 01/2023 - 03/2004
34	Inflammation (Inflammations) 11/2020 - 06/2003
30	Airway Remodeling 09/2019 - 02/2004
27	Fibrosis (Cirrhosis) 11/2020 - 02/2004
11	Eosinophilia 07/2017 - 05/2007
8	Respiratory Hypersensitivity 01/2023 - 07/2002
8	Eosinophilic Esophagitis 01/2016 - 08/2008
7	Pneumonia (Pneumonitis) 01/2017 - 05/2007
7	Allergic Rhinitis 01/2016 - 05/2005
7	Hypersensitivity (Allergy) 02/2013 - 01/2006
6	Hyperplasia 01/2021 - 05/2011
4	Chronic Obstructive Pulmonary Disease (COPD) 06/2011 - 11/2007
3	Emphysema 12/2010 - 11/2007
2	Lung Diseases (Lung Disease) 11/2020 - 06/2011
2	Infections 10/2017 - 01/2016
2	Hypoxia (Hypoxemia) 01/2017 - 04/2013
1	Hypertrophy 01/2021
1	Virus Diseases (Viral Diseases) 09/2019
1	Rhinosinusitis 01/2019
1	Common Variable Immunodeficiency 02/2017
1	Polyps 11/2014
1	Nasal Polyps (Nasal Polyp) 11/2014

Drug/Important Bio-Agent (IBA)

44	AllergensIBA 01/2023 - 06/2003
21	CytokinesIBA 01/2023 - 05/2004
16	OvalbuminIBA 01/2016 - 06/2003
14	CollagenIBA 11/2020 - 02/2004
9	Proteins (Proteins, Gene)FDA Link 01/2021 - 05/2005
9	Interleukin-13IBA 09/2019 - 02/2008
9	Interleukin-5 (Interleukin 5)IBA 01/2019 - 02/2004
9	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2016 - 06/2003
9	DNA (Deoxyribonucleic Acid)IBA 03/2006 - 07/2002
8	SmokeIBA 09/2019 - 04/2007
8	AntigensIBA 01/2016 - 08/2006
8	Immunoglobulin E (IgE)IBA 01/2015 - 11/2007
6	ChemokinesIBA 06/2014 - 12/2004
6	Sialic Acid Binding Immunoglobulin-like LectinsIBA 10/2011 - 05/2007
6	Transforming Growth Factor beta (TGF-beta)IBA 10/2009 - 02/2004
5	Transforming Growth Factors (Transforming Growth Factor)IBA 09/2019 - 05/2004
4	Interleukin-4 (Interleukin 4)IBA 01/2019 - 11/2007
4	Orosomucoid (Seromucoid)IBA 01/2018 - 10/2012
4	Fibronectins (Fibronectin)IBA 01/2016 - 11/2010
4	Extracellular Matrix ProteinsIBA 01/2014 - 03/2006
4	Chemokine CCL11IBA 01/2014 - 04/2007
4	LigandsIBA 11/2010 - 03/2004
3	LeukotrienesIBA 09/2019 - 07/2013
3	Interleukin-33IBA 09/2019 - 01/2016
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2019 - 03/2008
3	FollistatinIBA 01/2017 - 10/2015
3	Metalloproteases (Metalloproteinases)IBA 01/2016 - 03/2008
3	Methacholine Chloride (Methacholine)FDA Link 10/2012 - 05/2004
3	Inflammation MediatorsIBA 06/2011 - 03/2008
3	NF-kappa B (NF-kB)IBA 08/2010 - 12/2005
3	Transforming Growth Factor beta1 (TGF beta 1)IBA 01/2010 - 01/2006
2	Interleukin-9 (Interleukin 9)IBA 01/2022 - 06/2013
2	Small Interfering RNA (siRNA)IBA 01/2021 - 10/2012
2	Peroxidase (Myeloperoxidase)IBA 01/2017 - 06/2011
2	leukotriene D4 receptor (cysteinyl leukotriene receptor)IBA 01/2017 - 07/2013
2	Transcription Factors (Transcription Factor)IBA 01/2017 - 10/2012
2	Thymic Stromal LymphopoietinIBA 01/2016 - 09/2010
2	Immunoglobulin G (IgG)IBA 10/2012 - 05/2011
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2011 - 05/2011
2	Carbon MonoxideIBA 06/2011 - 11/2007
2	Biomarkers (Surrogate Marker)IBA 06/2011 - 11/2007
2	EnzymesIBA 06/2011 - 03/2006
2	AdiponectinIBA 12/2010 - 01/2009
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2010 - 05/2004
2	I-kappa B KinaseIBA 08/2010 - 12/2005
2	VaccinesIBA 01/2009 - 07/2002
2	Matrix Metalloproteinase 9 (Gelatinase B)IBA 03/2008 - 03/2006
1	Member 14 Tumor Necrosis Factor ReceptorsIBA 01/2023
1	Bromodeoxyuridine (BrdU)IBA 01/2021
1	Bleomycin (Blenoxane)FDA LinkGeneric 11/2020
1	Member 25 Tumor Necrosis Factor ReceptorsIBA 11/2020
1	Indicators and Reagents (Reagents)IBA 11/2020
1	Carrier Proteins (Binding Protein)IBA 01/2018
1	CalciumIBA 01/2018
1	2-5A-dependent ribonuclease (RNase L)IBA 10/2017
1	Antiviral Agents (Antivirals)IBA 10/2017
1	Prostaglandin D2IBA 07/2017
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 07/2017
1	Intravenous Immunoglobulins (IVIG)FDA Link 02/2017
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2017
1	Beclin-1IBA 01/2017
1	2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA 01/2017
1	LipidsIBA 01/2017
1	Interleukin-6 (Interleukin 6)IBA 01/2017
1	Leukotriene C4IBA 01/2017
1	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 11/2016
1	ProstaglandinsIBA 01/2016
1	OX40 LigandIBA 01/2016
1	Plasminogen Activator Inhibitor 1IBA 01/2016
1	VimentinIBA 01/2016
1	Forkhead Transcription Factors (Forkhead Box Proteins)IBA 01/2016
1	Oncostatin MIBA 10/2015
1	Cyclic AMP (AMP, Cyclic)IBA 02/2015
1	Tryptases (Tryptase)IBA 01/2015
1	phospholambanIBA 11/2014
1	Heparitin Sulfate (Heparan Sulfate)IBA 06/2014

Therapy/Procedure

12	Therapeutics 11/2020 - 05/2005
2	Immunotherapy 01/2006 - 05/2005